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A Phosphatidic Acid (PA) conveyor system of continuous intracellular transport from cell membrane to nucleus maintains EGF receptor homeostasis
The intracellular concentration of the mitogen phosphatidic acid (PA) must be maintained at low levels until the need arises for cell proliferation. How temporal and spatial trafficking of PA affects its target proteins in the different cellular compartments is not fully understood. We report that i...
Autores principales: | Henkels, Karen M., Miller, Taylor E., Ganesan, Ramya, Wilkins, Brandon A., Fite, Kristen, Gomez-Cambronero, Julian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216919/ https://www.ncbi.nlm.nih.gov/pubmed/27256981 http://dx.doi.org/10.18632/oncotarget.9685 |
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