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A pan-cancer analysis of MYC-PVT1 reveals CNV-unmediated deregulation and poor prognosis in renal carcinoma

The PVT1 lncRNA has recently been involved in tumorigenesis by affecting the protein stability of the MYC proto-oncogene. Both MYC and PVT1 reside in a well-known cancer-risk locus and enhanced levels of their products have been reported in different human cancers. Nonetheless, the extension and rel...

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Detalles Bibliográficos
Autores principales: Posa, Ioana, Carvalho, Silvia, Tavares, Joana, Grosso, Ana Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216921/
https://www.ncbi.nlm.nih.gov/pubmed/27366943
http://dx.doi.org/10.18632/oncotarget.9487