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Peroxiredoxin 1 promotes invasion and migration by regulating epithelial-to-mesenchymal transition during oral carcinogenesis

Tobacco smoking is the major risk factor for oral squamous cell carcinoma (OSCC). Previously, we found that nicotine up-regulates peroxiredoxin 1 (Prx1), an important antioxidant enzyme, and nuclear factor kappa B (NFκB) in OSCC cells. However, the molecular mechanism of Prx1 in oral carcinogenesis...

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Detalles Bibliográficos
Autores principales: Niu, Wenwen, Zhang, Min, Chen, Hui, Wang, Chunxiao, Shi, Ni, Jing, Xinying, Ge, Lihua, Chen, Tong, Tang, Xiaofei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216922/
https://www.ncbi.nlm.nih.gov/pubmed/27259998
http://dx.doi.org/10.18632/oncotarget.9705