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SOX2 is essential for in vivo reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate

Type II germ cell cancers (GCC) are divided into seminomas, which are highly similar to primordial germ cells and embryonal carcinomas (EC), often described as malignant counterparts to embryonic stem cells. Previously, we demonstrated that the development of GCCs is a highly plastic process and str...

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Detalles Bibliográficos
Autores principales: Nettersheim, Daniel, Heimsoeth, Alena, Jostes, Sina, Schneider, Simon, Fellermeyer, Martin, Hofmann, Andrea, Schorle, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216926/
https://www.ncbi.nlm.nih.gov/pubmed/27283990
http://dx.doi.org/10.18632/oncotarget.9903