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Reduction of estradiol in human malignant pleural mesothelioma tissues may prevent tumour growth, as implied by in in-vivo and in-vitro models

This study aimed to investigate intratumoural estradiol and estrogen-receptors (ERα, ERβ and GPR30) in malignant pleural mesothelioma (MPM) to understand their function. Here, we report that immunohistochemistry of estradiol showed cytoplasmatic staining in 95% of fifty-seven human MPM samples with...

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Detalles Bibliográficos
Autores principales: Nuvoli, Barbara, Sacconi, Andrea, Cortese, Giancarlo, Germoni, Sabrina, Murer, Bruno, Galati, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216928/
https://www.ncbi.nlm.nih.gov/pubmed/27323398
http://dx.doi.org/10.18632/oncotarget.9964