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Comprehensive genomic profiling of IgM multiple myeloma identifies IRF4 as a prognostic marker

Immunoglobulin M multiple myeloma (IgM MM) is an extremely rare subtype of multiple myeloma with a poor clinical outcome. In this study, bone marrow aspirates of MM patients, including two cases of IgM MM, were analyzed by whole exome sequencing and RNA sequencing. Recurrent somatic mutations in the...

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Detalles Bibliográficos
Autores principales: Ryu, Daeun, Kim, Hee Jin, Joung, Je-Gun, Lee, Hae-Ock, Bae, Joon Seol, Kim, Seok Jin, Kim, Haesu, Park, Woong-Yang, Kim, Kihyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216929/
https://www.ncbi.nlm.nih.gov/pubmed/27223072
http://dx.doi.org/10.18632/oncotarget.9478