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Albuminuria enhances NHE3 and NCC via stimulation of mitochondrial oxidative stress/angiotensin II axis

Imbalance of salt and water is a frequent and challenging complication of kidney disease, whose pathogenic mechanisms remain elusive. Employing an albumin overload mouse model, we discovered that albuminuria enhanced the expression of NHE3 and NCC but not other transporters in murine kidney in line...

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Detalles Bibliográficos
Autores principales: Jia, Zhanjun, Zhuang, Yibo, Hu, Caiyu, Zhang, Xintong, Ding, Guixia, Zhang, Yue, Rohatgi, Rajeev, Hua, Hu, Huang, Songming, He, John Ci-jiang, Zhang, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216930/
https://www.ncbi.nlm.nih.gov/pubmed/27323402
http://dx.doi.org/10.18632/oncotarget.9972