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Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms

Human papillomavirus (HPV) causes cervical cancer and a large fraction of head and neck squamous cell carcinomas (HNSCC). Cidofovir (CDV) proved efficacious in the treatment of several HPV-induced benign and malignant hyper proliferations. To provide a better insight into how CDV selectively eradica...

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Detalles Bibliográficos
Autores principales: Mertens, Barbara, Nogueira, Tatiane, Stranska, Ruzena, Naesens, Lieve, Andrei, Graciela, Snoeck, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216943/
https://www.ncbi.nlm.nih.gov/pubmed/27331622
http://dx.doi.org/10.18632/oncotarget.10100