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Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer

Epithelial ovarian cancer (EOC) is the most lethal gynecological cancer and often is not detected until late stages when cancer cells transcoelomically metastasize to the abdomen and typically become resistant to therapy resulting in very low survival rates. We utilize an orthotopic, syngeneic mouse...

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Detalles Bibliográficos
Autores principales: Greenaway, James B., Virtanen, Carl, Osz, Kata, Revay, Tamas, Hardy, Daniel, Shepherd, Trevor, DiMattia, Gabriel, Petrik, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216946/
https://www.ncbi.nlm.nih.gov/pubmed/27329838
http://dx.doi.org/10.18632/oncotarget.10121