Phosphorylation of mTOR Ser2481 is a key target limiting the efficacy of rapalogs for treating hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Although recent studies facilitate the identification of crucial genes and relevant regulatory pathways, therapeutic approaches against advanced HCC are insufficiently effective. Therefore, we aimed here to develop potent th...

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Detalles Bibliográficos
Autores principales: Watari, Kosuke, Nishitani, Ayumi, Shibata, Tomohiro, Noda, Masaki, Kawahara, Akihiko, Akiba, Jun, Murakami, Yuichi, Yano, Hirohisa, Kuwano, Michihiko, Ono, Mayumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216950/
https://www.ncbi.nlm.nih.gov/pubmed/27329724
http://dx.doi.org/10.18632/oncotarget.10161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216950/
https://www.ncbi.nlm.nih.gov/pubmed/27329724
http://dx.doi.org/10.18632/oncotarget.10161

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