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MMP7 interacts with ARF in nucleus to potentiate tumor microenvironments for prostate cancer progression in vivo

ARF couples with TP53 in a canonical signaling pathway to activate cellular senescence for tumor suppressive function under oncogenic insults. However, the mechanisms on aberrant elevation of ARF in cancers are still poorly understood. We previously showed that ARF (p14(ARF) in human and p19(Arf) in...

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Detalles Bibliográficos
Autores principales: Xie, Yingqiu, Lu, Wenfu, Liu, Shenji, Yang, Qing, Goodwin, J. Shawn, Sathyanarayana, Sandeep Anantha, Pratap, Siddharth, Chen, Zhenbang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216965/
https://www.ncbi.nlm.nih.gov/pubmed/27356744
http://dx.doi.org/10.18632/oncotarget.10251