CCR4 promotes metastasis via ERK/NF-κB/MMP13 pathway and acts downstream of TNF-α in colorectal cancer

Chemokines and chemokine receptors are causally involved in the metastasis of human malignancies. As a crucial chemokine receptor for mediating immune homeostasis, however, the role of CCR4 in colorectal cancer (CRC) remains unknown. In this study, we found that high expression of CCR4 in CRC tissue...

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Detalles Bibliográficos
Autores principales: Ou, Baochi, Zhao, Jingkun, Guan, Shaopei, Feng, Hao, Wangpu, Xiongzhi, Zhu, Congcong, Zong, Yaping, Ma, Junjun, Sun, Jing, Shen, Xiaohui, Zheng, Minhua, Lu, Aiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216967/
https://www.ncbi.nlm.nih.gov/pubmed/27356745
http://dx.doi.org/10.18632/oncotarget.10256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216967/
https://www.ncbi.nlm.nih.gov/pubmed/27356745
http://dx.doi.org/10.18632/oncotarget.10256

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