MicroRNA-27a promotes renal tubulointerstitial fibrosis via suppressing PPARγ pathway in diabetic nephropathy

MicroRNA-27a (miR-27a) upregulation has been identified in diabetes, but the pathogenesis of miR-27a in renal tubulointerstitial fibrosis (TIF) in diabetic nephropathy (DN) has not been elucidated. Herein, we found that high glucose stimulated miR-27a expression, which directly inhibited PPARγ and p...

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Detalles Bibliográficos
Autores principales: Hou, Xiaoyan, Tian, Jianwei, Geng, Jian, Li, Xiao, Tang, Xun, Zhang, Jun, Bai, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216977/
https://www.ncbi.nlm.nih.gov/pubmed/27351287
http://dx.doi.org/10.18632/oncotarget.10283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216977/
https://www.ncbi.nlm.nih.gov/pubmed/27351287
http://dx.doi.org/10.18632/oncotarget.10283

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