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Epidermal growth factor receptor inhibitors trigger a type I interferon response in human skin

The Epidermal Growth Factor Receptor (EGFR) is centrally involved in the regulation of key processes of the epithelia, including cell proliferation, survival, differentiation, and also tumorigenesis. Humanized antibodies and small-molecule inhibitors targeting EGFR were developed to disrupt these fu...

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Detalles Bibliográficos
Autores principales: Lulli, Daniela, Carbone, Maria Luigia, Pastore, Saveria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216978/
https://www.ncbi.nlm.nih.gov/pubmed/27322144
http://dx.doi.org/10.18632/oncotarget.10013