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Prolactin signaling through focal adhesion complexes is amplified by stiff extracellular matrices in breast cancer cells

Estrogen receptor α positive (ERα+) breast cancer accounts for most breast cancer deaths. Both prolactin (PRL) and extracellular matrix (ECM) stiffness/density have been implicated in metastatic progression of this disease. We previously demonstrated that these factors cooperate to fuel processes in...

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Detalles Bibliográficos
Autores principales: Barcus, Craig E., Keely, Patricia J., Eliceiri, Kevin W., Schuler, Linda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217003/
https://www.ncbi.nlm.nih.gov/pubmed/27344177
http://dx.doi.org/10.18632/oncotarget.10137