Downregulation of HP1α suppresses proliferation of cholangiocarcinoma by restoring SFRP1 expression

Heterochromatin protein 1α (HP1α) is a gene that mediates chromatin conformation, gene silencing and cancer progression. However, little is known regarding the impact of HP1α in the pathogenesis of cholangiocarcinoma (CCA). In the present study, we demonstrate that HP1α is significantly upregulated...

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Detalles Bibliográficos
Autores principales: Cheng, Wenlong, Tian, Li, Wang, Bing, Qi, Yongqiang, Huang, Wenhua, Li, Hongbo, Chen, Yong-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217004/
https://www.ncbi.nlm.nih.gov/pubmed/27385214
http://dx.doi.org/10.18632/oncotarget.10371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217004/
https://www.ncbi.nlm.nih.gov/pubmed/27385214
http://dx.doi.org/10.18632/oncotarget.10371

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