MT2-MMP induces proteolysis and leads to EMT in carcinomas

Epithelial-mesenchymal transition (EMT) is critical for carcinoma invasiveness and metastasis. To investigate the role of membrane-type-2 matrix metalloproteinase (MT2-MMP) in EMT, we generated lentiviral constructs of wild-type (WT) and an inactive Glu260Ala (E260A) mutant MT2-MMP and derived stabl...

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Detalles Bibliográficos
Autores principales: Liu, Yusi, Sun, Xiaojiao, Feng, Jinfa, Deng, Li-Li, Liu, Yihao, Li, Bokang, Zhu, Mingyue, Lu, Changlian, Zhou, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217011/
https://www.ncbi.nlm.nih.gov/pubmed/27374080
http://dx.doi.org/10.18632/oncotarget.10194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217011/
https://www.ncbi.nlm.nih.gov/pubmed/27374080
http://dx.doi.org/10.18632/oncotarget.10194

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