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Suppression of APC/C(Cdh1) has subtype specific biological effects in acute myeloid leukemia
The E3 ubiquitin ligase and tumor suppressor APC/C(Cdh1) is crucial for cell cycle progression, development and differentiation in many cell types. However, little is known about the role of Cdh1 in hematopoiesis. Here we analyzed Cdh1 expression and function in malignant hematopoiesis. We found a s...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217013/ https://www.ncbi.nlm.nih.gov/pubmed/27374082 http://dx.doi.org/10.18632/oncotarget.10196 |