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Mesenchymal stem cells promote osteosarcoma cell survival and drug resistance through activation of STAT3

Increasing evidence suggests that the tumor microenvironment plays a key role in the development of drug resistant tumor cells. In this study, we tried to determine whether the mesenchymal stem cells (MSCs) in the tumor microenvironment contribute to the increased chemoresistance of osteosarcoma. We...

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Detalles Bibliográficos
Autores principales: Tu, Bing, Zhu, Jing, Liu, Shen, Wang, Lei, Fan, Qiming, Hao, Yongqiang, Fan, Cunyi, Tang, Ting-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217018/
https://www.ncbi.nlm.nih.gov/pubmed/27340780
http://dx.doi.org/10.18632/oncotarget.10219