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Mesenchymal stem cells promote osteosarcoma cell survival and drug resistance through activation of STAT3
Increasing evidence suggests that the tumor microenvironment plays a key role in the development of drug resistant tumor cells. In this study, we tried to determine whether the mesenchymal stem cells (MSCs) in the tumor microenvironment contribute to the increased chemoresistance of osteosarcoma. We...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217018/ https://www.ncbi.nlm.nih.gov/pubmed/27340780 http://dx.doi.org/10.18632/oncotarget.10219 |