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Aurora kinase A revives dormant laryngeal squamous cell carcinoma cells via FAK/PI3K/Akt pathway activation

Revival of dormant tumor cells may be an important tumor metastasis mechanism. We hypothesized that aurora kinase A (AURKA), a cell cycle control kinase, promotes the transition of laryngeal squamous cell carcinoma (LSCC) cells from G0 phase to active division. We therefore investigated whether AURK...

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Detalles Bibliográficos
Autores principales: Yang, Li-yun, He, Chang-yu, Chen, Xue-hua, Su, Li-ping, Liu, Bing-ya, Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217022/
https://www.ncbi.nlm.nih.gov/pubmed/27356739
http://dx.doi.org/10.18632/oncotarget.10233