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MicroRNA-106b~25 cluster is upregulated in relapsed MLL-rearranged pediatric acute myeloid leukemia

The most important reason for therapy failure in pediatric acute myeloid leukemia (AML) is relapse. In order to identify miRNAs that contribute to the clonal evolution towards relapse in pediatric AML, miRNA expression profiling of 127 de novo pediatric AML cases were used. In the diagnostic phase,...

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Detalles Bibliográficos
Autores principales: Verboon, Lonneke J., Obulkasim, Askar, de Rooij, Jasmijn D.E., Katsman, Jenny E., Sonneveld, Edwin, Baruchel, André, Trka, Jan, Reinhardt, Dirk, Pieters, Rob, Cloos, Jacqueline, Kaspers, Gertjan J.L., Klusmann, Jan-Henning, Zwaan, Christian Michel, Fornerod, Maarten, van den Heuvel-Eibrink, Marry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217027/
https://www.ncbi.nlm.nih.gov/pubmed/27351222
http://dx.doi.org/10.18632/oncotarget.10270