The anti-tumor efficacy of 3-(2-Nitrophenyl) propionic acid-paclitaxel (NPPA-PTX): a novel paclitaxel bioreductive prodrug

Hypoxia is an important microenvironmental pressure present in the majority of solid tumors and, so, tumor hypoxia might be considered an attractive target for tumor therapy. One strategy for targeting hypoxia is to develop bioreductive prodrugs. In the present research, we synthesized a bioreductiv...

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Detalles Bibliográficos
Autores principales: Song, Ping, Yao, Xin, Zhong, Ting, Zhang, Shuang, Guo, Yang, Ren, Wei, Huang, Dan, Duan, Xiao-Chuan, Yin, Yi-Fan, Zhang, Shu-Shi, Zhang, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217032/
https://www.ncbi.nlm.nih.gov/pubmed/27366947
http://dx.doi.org/10.18632/oncotarget.10310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217032/
https://www.ncbi.nlm.nih.gov/pubmed/27366947
http://dx.doi.org/10.18632/oncotarget.10310

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