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Inhibition of ERα/ERK/P62 cascades induces “autophagic switch” in the estrogen receptor-positive breast cancer cells exposed to gemcitabine

Several clinical trials revealed that estrogen receptor (ER) status had relevance to the response of mammary malignancy to chemotherapy. Autophagy has emerged as an important cellular mechanism of tumor cells in response to anticancer therapy. The aim of this study is to investigate whether gemcitab...

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Detalles Bibliográficos
Autores principales: Shen, Peng, Chen, Ming, He, Mengye, Chen, Luoquan, Song, Yinjing, Xiao, Peng, Wan, Xiaopeng, Dai, Feng, Pan, Ting, Wang, Qingqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217034/
https://www.ncbi.nlm.nih.gov/pubmed/27384485
http://dx.doi.org/10.18632/oncotarget.10363