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Inhibition of ERα/ERK/P62 cascades induces “autophagic switch” in the estrogen receptor-positive breast cancer cells exposed to gemcitabine
Several clinical trials revealed that estrogen receptor (ER) status had relevance to the response of mammary malignancy to chemotherapy. Autophagy has emerged as an important cellular mechanism of tumor cells in response to anticancer therapy. The aim of this study is to investigate whether gemcitab...
Autores principales: | Shen, Peng, Chen, Ming, He, Mengye, Chen, Luoquan, Song, Yinjing, Xiao, Peng, Wan, Xiaopeng, Dai, Feng, Pan, Ting, Wang, Qingqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217034/ https://www.ncbi.nlm.nih.gov/pubmed/27384485 http://dx.doi.org/10.18632/oncotarget.10363 |
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