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miR-130b, an onco-miRNA in bladder cancer, is directly regulated by NF-κB and sustains NF-κB activation by decreasing Cylindromatosis expression

Persistent activation of NF-κB signaling is closely related to chronic inflammation and tumorigenesis. Commonly, NF-κB signaling is tightly controlled by multiple feedback loops and regulators, such as the deubiquitinases (DUBs). However, in cancer cells, NF-κB may override these feedbacks through s...

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Detalles Bibliográficos
Autores principales: Cui, Xiaolu, Kong, Chuize, Zhu, Yuyan, Zeng, Yu, Zhang, Zhe, Liu, Xiankui, Zhan, Bo, Piao, Chiyuan, Jiang, Zhenming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217037/
https://www.ncbi.nlm.nih.gov/pubmed/27391066
http://dx.doi.org/10.18632/oncotarget.10423