Paclitaxel is necessary for improved survival in epithelial ovarian cancers with homologous recombination gene mutations

PURPOSE: To investigate the impact of somatic mutations in homologous recombination (HR) genes on the chemotherapeutic response and survival of patients with epithelial ovarian cancer (EOC). EXPERIMENTAL DESIGN: We performed targeted massively parallel sequencing of tumor DNA from 158 patients with...

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Detalles Bibliográficos
Autores principales: Jean, Stephanie, Li, Jiaqi, Katsaros, Dionyssios, Wubbenhorst, Bradley, Maxwell, Kara N., Fishbein, Lauren, McLane, Michael W., Benedetto, Chiara, Canuto, Emilie Marion, Mitra, Nandita, Zhang, Lin, Nathanson, Katherine L., Tanyi, Janos L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Clinical Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217039/
https://www.ncbi.nlm.nih.gov/pubmed/27191893
http://dx.doi.org/10.18632/oncotarget.9373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217039/
https://www.ncbi.nlm.nih.gov/pubmed/27191893
http://dx.doi.org/10.18632/oncotarget.9373

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