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KIFC1: a promising chemotherapy target for cancer treatment?

The kinesin motor KIFC1 has been suggested as a potential chemotherapy target due to its critical role in clustering of the multiple centrosomes found in cancer cells. In this regard, KIFC1 seems to be non-essential in normal somatic cells which usually possess only two centrosomes. Moreover, KIFC1...

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Detalles Bibliográficos
Autores principales: Xiao, Yu-Xi, Yang, Wan-Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217046/
https://www.ncbi.nlm.nih.gov/pubmed/27102297
http://dx.doi.org/10.18632/oncotarget.8799