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BPA‐toxicity via superoxide anion overload and a deficit in β‐catenin signaling in human bone mesenchymal stem cells

Bisphenol A (BPA), used in the manufacture of products based on polycarbonate plastics and epoxy resins, is well known as an endocrine‐disrupting monomer. In the current study, BPA increased cytotoxicity in hBMSCs in a dose‐ and time‐dependent manner, concomitantly with increased lipid peroxidation....

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Detalles Bibliográficos
Autores principales: Leem, Yea‐Hyun, Oh, Seikwan, Kang, Hong‐Je, Kim, Jung‐Hwa, Yoon, Juno, Chang, Jae‐Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217073/
https://www.ncbi.nlm.nih.gov/pubmed/26822619
http://dx.doi.org/10.1002/tox.22239