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Simultaneous assessment of cardiac metabolism and perfusion using copolarized [1‐(13)C]pyruvate and (13)C‐urea

PURPOSE: To demonstrate the feasibility of imaging a bolus of co‐polarized [1‐(13)C]pyruvate and (13)C‐urea to simultaneously assess both metabolism and perfusion in the rodent heart. METHODS: Copolarized [1‐(13)C]pyruvate and (13)C‐urea was imaged using a multi‐echo, flow‐sensitized spiral pulse se...

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Detalles Bibliográficos
Autores principales: Lau, Angus Z., Miller, Jack J., Robson, Matthew D., Tyler, Damian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217077/
https://www.ncbi.nlm.nih.gov/pubmed/26743440
http://dx.doi.org/10.1002/mrm.26106