Cargando…
Weighted analysis of composite endpoints with simultaneous inference for flexible weight constraints
Composite endpoints are widely used as primary endpoints of randomized controlled trials across clinical disciplines. A common critique of the conventional analysis of composite endpoints is that all disease events are weighted equally, whereas their clinical relevance may differ substantially. We a...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217097/ https://www.ncbi.nlm.nih.gov/pubmed/27782312 http://dx.doi.org/10.1002/sim.7147 |