Caenorhabditis elegans DAF-2 as a Model for Human Insulin Receptoropathies

Human exome sequencing has dramatically increased the rate of identification of disease-associated polymorphisms. However, examining the functional consequences of those variants has created an analytic bottleneck. Insulin-like signaling in Caenorhabditis elegans has long provided a model to assess...

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Detalles Bibliográficos
Autores principales: Bulger, David A., Fukushige, Tetsunari, Yun, Sijung, Semple, Robert K., Hanover, John A., Krause, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217114/
https://www.ncbi.nlm.nih.gov/pubmed/27856697
http://dx.doi.org/10.1534/g3.116.037184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217114/
https://www.ncbi.nlm.nih.gov/pubmed/27856697
http://dx.doi.org/10.1534/g3.116.037184

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