Combination of alpha-synuclein immunotherapy with anti-inflammatory treatment in a transgenic mouse model of multiple system atrophy

Multiple system atrophy (MSA) is a fatal neurodegenerative disorder characterized by the pathological accumulation of alpha-synuclein (α-syn) in oligodendrocytes. Therapeutic efforts to stop or delay the progression of MSA have yielded suboptimal results in clinical trials, and there are no efficien...

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Detalles Bibliográficos
Autores principales: Valera, Elvira, Spencer, Brian, Fields, Jerel A., Trinh, Ivy, Adame, Anthony, Mante, Michael, Rockenstein, Edward, Desplats, Paula, Masliah, Eliezer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217191/
https://www.ncbi.nlm.nih.gov/pubmed/28057080
http://dx.doi.org/10.1186/s40478-016-0409-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217191/
https://www.ncbi.nlm.nih.gov/pubmed/28057080
http://dx.doi.org/10.1186/s40478-016-0409-1

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