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Treatment of intermittent hypoxia increases phosphorylated tau in the hippocampus via biological processes common to aging

Sleep-disordered breathing produces cognitive impairments, and is possibly associated with Alzheimer disease (AD). Intermittent hypoxia treatment (IHT), an experimental model for sleep-disordered breathing, results in cognitive impairments in animals via unknown mechanisms. Here, we exposed mice to...

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Detalles Bibliográficos
Autores principales: Yagishita, Sosuke, Suzuki, Seiya, Yoshikawa, Keisuke, Iida, Keiko, Hirata, Ayako, Suzuki, Masahiko, Takashima, Akihiko, Maruyama, Kei, Hirasawa, Akira, Awaji, Takeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217192/
https://www.ncbi.nlm.nih.gov/pubmed/28057021
http://dx.doi.org/10.1186/s13041-016-0282-7