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Treatment of intermittent hypoxia increases phosphorylated tau in the hippocampus via biological processes common to aging
Sleep-disordered breathing produces cognitive impairments, and is possibly associated with Alzheimer disease (AD). Intermittent hypoxia treatment (IHT), an experimental model for sleep-disordered breathing, results in cognitive impairments in animals via unknown mechanisms. Here, we exposed mice to...
Autores principales: | Yagishita, Sosuke, Suzuki, Seiya, Yoshikawa, Keisuke, Iida, Keiko, Hirata, Ayako, Suzuki, Masahiko, Takashima, Akihiko, Maruyama, Kei, Hirasawa, Akira, Awaji, Takeo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217192/ https://www.ncbi.nlm.nih.gov/pubmed/28057021 http://dx.doi.org/10.1186/s13041-016-0282-7 |
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