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Distinct pattern of enteric phospho-alpha-synuclein aggregates and gene expression profiles in patients with Parkinson’s disease

Phosphorylated alpha-synuclein (p-α-syn) containing Lewy bodies (LBs) and Lewy neurites (LNs) are neuropathological hallmarks of Parkinson’s disease (PD) in the central nervous system (CNS). Since they have been also demonstrated in the enteric nervous system (ENS) of PD patients, the aim of the stu...

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Detalles Bibliográficos
Autores principales: Barrenschee, Martina, Zorenkov, Dimitri, Böttner, Martina, Lange, Christina, Cossais, François, Scharf, Amelie Bernadette, Deuschl, Günther, Schneider, Susanne A., Ellrichmann, Mark, Fritscher-Ravens, Annette, Wedel, Thilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217296/
https://www.ncbi.nlm.nih.gov/pubmed/28057070
http://dx.doi.org/10.1186/s40478-016-0408-2