Cargando…

Distinct pattern of enteric phospho-alpha-synuclein aggregates and gene expression profiles in patients with Parkinson’s disease

Phosphorylated alpha-synuclein (p-α-syn) containing Lewy bodies (LBs) and Lewy neurites (LNs) are neuropathological hallmarks of Parkinson’s disease (PD) in the central nervous system (CNS). Since they have been also demonstrated in the enteric nervous system (ENS) of PD patients, the aim of the stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barrenschee, Martina, Zorenkov, Dimitri, Böttner, Martina, Lange, Christina, Cossais, François, Scharf, Amelie Bernadette, Deuschl, Günther, Schneider, Susanne A., Ellrichmann, Mark, Fritscher-Ravens, Annette, Wedel, Thilo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217296/ https://www.ncbi.nlm.nih.gov/pubmed/28057070 http://dx.doi.org/10.1186/s40478-016-0408-2

Ejemplares similares

Morphologic Basis for Developing Diverticular Disease, Diverticulitis, and Diverticular Bleeding
por: Wedel, Thilo, et al.
Publicado: (2015)

Expression and function of Neuregulin 1 and its signaling system ERBB2/3 in the enteric nervous system
por: Barrenschee, Martina, et al.
Publicado: (2015)

Impaired Expression of Neuregulin 1 and Nicotinic Acetylcholine Receptor β4 Subunit in Diverticular Disease
por: Barrenschee, Martina, et al.
Publicado: (2019)

No neuronal loss, but alterations of the GDNF system in asymptomatic diverticulosis
por: Barrenschee, Martina, et al.
Publicado: (2017)

The GDNF System Is Altered in Diverticular Disease – Implications for Pathogenesis
por: Böttner, Martina, et al.
Publicado: (2013)

Localization Pattern of Dispatched Homolog 2 (DISP2) in the Central and Enteric Nervous System
por: Heimke, Marvin, et al.
Publicado: (2023)

Alpha Synuclein Connects the Gut-Brain Axis in Parkinson’s Disease Patients – A View on Clinical Aspects, Cellular Pathology and Analytical Methodology
por: Schaeffer, Eva, et al.
Publicado: (2020)

Limited Impact of 6-Mercaptopurine on Inflammation-Induced Chemokines Expression Profile in Primary Cultures of Enteric Nervous System
por: Kneusels, Jan, et al.
Publicado: (2021)

Aggregation of alpha-synuclein in enteric neurons does not impact function in vitro
por: Bindas, Adam J., et al.
Publicado: (2022)

NOTES and the mediastinum
por: Fritscher-Ravens, Annette
Publicado: (2015)

White Matter Changes Along the Electrode Lead in Patients Treated With Deep Brain Stimulation
por: Erasmi, Richard, et al.
Publicado: (2018)

The Aggregation of Huntingtin and α-Synuclein
por: Chánez-Cárdenas, María Elena, et al.
Publicado: (2012)

Monitoring α-synuclein aggregation
por: Estaun-Panzano, Juan, et al.
Publicado: (2023)

Effects of the TLR2 Agonists MALP-2 and Pam(3)Cys in Isolated Mouse Lungs
por: Barrenschee, Martina, et al.
Publicado: (2010)

Dermal Phospho-Alpha-Synuclein Deposition in Patients With Parkinson's Disease and Mutation of the Glucocerebrosidase Gene
por: Doppler, Kathrin, et al.
Publicado: (2018)

Expression of estrogen receptors in the hypothalamo-pituitary-ovarian axis in middle-aged rats after re-instatement of estrus cyclicity
por: Böttner, M., et al.
Publicado: (2009)

SUMOylation of Alpha-Synuclein Influences on Alpha-Synuclein Aggregation Induced by Methamphetamine
por: Zhu, Lin-nan, et al.
Publicado: (2018)

Phospho-S129 Alpha-Synuclein Is Present in Human Plasma but Not in Cerebrospinal Fluid as Determined by an Ultrasensitive Immunoassay
por: Cariulo, Cristina, et al.
Publicado: (2019)

Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversity
por: Lashuel, Hilal A., et al.
Publicado: (2022)

Acceleration of α-Synuclein Aggregation by Exosomes
por: Grey, Marie, et al.
Publicado: (2015)

Alpha-Synuclein Aggregation in Parkinson's Disease
por: Srinivasan, E., et al.
Publicado: (2021)

Aggregation and neurotoxicity of recombinant α-synuclein aggregates initiated by dimerization
por: Roostaee, Alireza, et al.
Publicado: (2013)

Unveiling a Selective Mechanism for the Inhibition of α-Synuclein Aggregation by β-Synuclein
por: Leitao, Andre, et al.
Publicado: (2018)

Synuclein Family Members Prevent Membrane Damage by Counteracting α-Synuclein Aggregation
por: Scheibe, Christian, et al.
Publicado: (2021)

Synthesis and Preliminary Characterization of Putative Anle138b-Centered PROTACs against α-Synuclein Aggregation
por: Pedrini, Martina, et al.
Publicado: (2023)

Dopamine Transporter, PhosphoSerine129 α-Synuclein and α-Synuclein Levels in Aged LRRK2 G2019S Knock-In and Knock-Out Mice
por: Domenicale, Chiara, et al.
Publicado: (2022)

Dermal phospho-alpha-synuclein deposits confirm REM sleep behaviour disorder as prodromal Parkinson’s disease
por: Doppler, Kathrin, et al.
Publicado: (2017)

Phospho-HDAC6 Gathers Into Protein Aggregates in Parkinson’s Disease and Atypical Parkinsonisms
por: Mazzetti, Samanta, et al.
Publicado: (2020)

Sumoylation inhibits α-synuclein aggregation and toxicity
por: Krumova, Petranka, et al.
Publicado: (2011)

Modulation of Alpha-Synuclein Aggregation by Dopamine Analogs
por: Latawiec, Diane, et al.
Publicado: (2010)

Models of α-synuclein aggregation in Parkinson’s disease
por: Giráldez-Pérez, Rosa María, et al.
Publicado: (2014)

Insights Into Peptide Inhibition of Alpha-Synuclein Aggregation
por: Torpey, James H., et al.
Publicado: (2020)

The Effects of Lipids on α-Synuclein Aggregation In Vitro
por: Ramirez, Jennifer, et al.
Publicado: (2023)

Modulation of lipopolysaccharide-induced neuronal response by activation of the enteric nervous system
por: Coquenlorge, Sabrina, et al.
Publicado: (2014)

In situ kinetic measurements of α-synuclein aggregation reveal large population of short-lived oligomers
por: Zurlo, Enrico, et al.
Publicado: (2021)

Inducing α-synuclein compaction: a new strategy for inhibiting α-synuclein aggregation?
por: Pinheiro, Francisca, et al.
Publicado: (2019)

Alpha-Synuclein FRET Biosensors Reveal Early Alpha-Synuclein Aggregation in the Endoplasmic Reticulum
por: Miraglia, Fabiana, et al.
Publicado: (2020)

Blocking the FKBP12 induced dendrimeric burst in aberrant aggregation of α-synuclein by using the ElteN378 synthetic inhibitor
por: Caminati, Gabriella, et al.
Publicado: (2019)

Monitoring α-synuclein Aggregation Induced by Preformed α-synuclein Fibrils in an In Vitro Model System
por: Kim, Beom Jin, et al.
Publicado: (2023)

Membrane Lipid Co-Aggregation with α-Synuclein Fibrils
por: Hellstrand, Erik, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_6tao7pic214buqano2n8tpl9oc