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Human LH and hCG stimulate differently the early signalling pathways but result in equal testosterone synthesis in mouse Leydig cells in vitro

BACKGROUND: Human luteinizing hormone (LH) and chorionic gonadotropin (hCG) are glycoprotein hormones regulating development and reproductive functions by acting on the same receptor (LHCGR). We compared the LH and hCG activity in gonadal cells from male mouse in vitro, i.e. primary Leydig cells, wh...

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Detalles Bibliográficos
Autores principales: Riccetti, Laura, De Pascali, Francesco, Gilioli, Lisa, Potì, Francesco, Giva, Lavinia Beatrice, Marino, Marco, Tagliavini, Simonetta, Trenti, Tommaso, Fanelli, Flaminia, Mezzullo, Marco, Pagotto, Uberto, Simoni, Manuela, Casarini, Livio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217336/
https://www.ncbi.nlm.nih.gov/pubmed/28056997
http://dx.doi.org/10.1186/s12958-016-0224-3