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Mass Spectrometric Immunoassays in Characterization of Clinically Significant Proteoforms

Proteins can exist as multiple proteoforms in vivo, as a result of alternative splicing and single-nucleotide polymorphisms (SNPs), as well as posttranslational processing. To address their clinical significance in a context of diagnostic information, proteoforms require a more in-depth analysis. Ma...

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Detalles Bibliográficos
Autores principales: Trenchevska, Olgica, Nelson, Randall W., Nedelkov, Dobrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217360/
https://www.ncbi.nlm.nih.gov/pubmed/28248223
http://dx.doi.org/10.3390/proteomes4010013