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XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell

BACKGROUND: The X-linked inhibitor of apoptosis protein (XIAP) is a well-known potent apoptosis suppressor and also participates in cancer cell biological behaviors, therefore attracting great attentions as a potential antineoplastic therapeutic target for past years. Anti-IAP therapy is reported to...

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Detalles Bibliográficos
Autores principales: Huang, Chao, Zeng, Xingruo, Jiang, Guosong, Liao, Xin, Liu, Claire, Li, Jingxia, Jin, Honglei, Zhu, Junlan, Sun, Hong, Wu, Xue-Ru, Huang, Chuanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217641/
https://www.ncbi.nlm.nih.gov/pubmed/28057023
http://dx.doi.org/10.1186/s13045-016-0376-9