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Identification of coding and non-coding mutational hotspots in cancer genomes

BACKGROUND: The identification of mutations that play a causal role in tumour development, so called “driver” mutations, is of critical importance for understanding how cancers form and how they might be treated. Several large cancer sequencing projects have identified genes that are recurrently mut...

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Detalles Bibliográficos
Autores principales: Piraino, Scott W., Furney, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217664/
https://www.ncbi.nlm.nih.gov/pubmed/28056774
http://dx.doi.org/10.1186/s12864-016-3420-9