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Evolutionary Adaptation of the Essential tRNA Methyltransferase TrmD to the Signaling Molecule 3′,5′-cAMP in Bacteria

The nucleotide signaling molecule 3′,5′-cyclic adenosine monophosphate (3′,5′-cAMP) plays important physiological roles, ranging from carbon catabolite repression in bacteria to mediating the action of hormones in higher eukaryotes, including human. However, it remains unclear whether 3′,5′-cAMP is...

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Detalles Bibliográficos
Autores principales: Zhang, Yong, Agrebi, Rym, Bellows, Lauren E., Collet, Jean-François, Kaever, Volkhard, Gründling, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217690/
https://www.ncbi.nlm.nih.gov/pubmed/27881678
http://dx.doi.org/10.1074/jbc.M116.758896