Anti‐inflammatory effects of infliximab in mice are independent of tumour necrosis factor α neutralization

Infliximab (IFX) has been used repeatedly in mouse preclinical models with associated claims that anti‐inflammatory effects are due to inhibition of mouse tumour necrosis factor (TNF)‐α. However, the mechanism of action in mice remains unclear. In this study, the binding specificity of IFX for mouse...

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Detalles Bibliográficos
Autores principales: Assas, B. M., Levison, S. E., Little, M., England, H., Battrick, L., Bagnall, J., McLaughlin, J. T., Paszek, P., Else, K. J., Pennock, J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217947/
https://www.ncbi.nlm.nih.gov/pubmed/27669117
http://dx.doi.org/10.1111/cei.12872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217947/
https://www.ncbi.nlm.nih.gov/pubmed/27669117
http://dx.doi.org/10.1111/cei.12872

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