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Contrast-Enhanced Ultrasound with VEGFR2-Targeted Microbubbles for Monitoring Regorafenib Therapy Effects in Experimental Colorectal Adenocarcinomas in Rats with DCE-MRI and Immunohistochemical Validation

OBJECTIVES: To investigate contrast-enhanced ultrasound (CEUS) with VEGFR2-targeted microbubbles for monitoring therapy effects of regorafenib on experimental colon carcinomas in rats with correlation to dynamic contrast-enhanced MRI (DCE-MRI) and immunohistochemistry. MATERIALS AND METHODS: Human c...

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Detalles Bibliográficos
Autores principales: Eschbach, Ralf Stefan, Clevert, Dirk-Andre, Hirner-Eppeneder, Heidrun, Ingrisch, Michael, Moser, Matthias, Schuster, Jessica, Tadros, Dina, Schneider, Moritz, Kazmierczak, Philipp Maximilian, Reiser, Maximilian, Cyran, Clemens C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217974/
https://www.ncbi.nlm.nih.gov/pubmed/28060884
http://dx.doi.org/10.1371/journal.pone.0169323