The Effector Domain Region of the Vibrio vulnificus MARTX Toxin Confers Biphasic Epithelial Barrier Disruption and Is Essential for Systemic Spread from the Intestine

Vibrio vulnificus causes highly lethal bacterial infections in which the Multifunctional Autoprocessing Repeats-in-Toxins (MARTX) toxin product of the rtxA1 gene is a key virulence factor. MARTX toxins are secreted proteins up to 5208 amino acids in size. Conserved MARTX N- and C-terminal repeat reg...

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Detalles Bibliográficos
Autores principales: Gavin, Hannah E., Beubier, Nike T., Satchell, Karla J. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218395/
https://www.ncbi.nlm.nih.gov/pubmed/28060924
http://dx.doi.org/10.1371/journal.ppat.1006119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218395/
https://www.ncbi.nlm.nih.gov/pubmed/28060924
http://dx.doi.org/10.1371/journal.ppat.1006119

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