Human S100A7 Induces Mature Interleukin1α Expression by RAGE-p38 MAPK-Calpain1 Pathway in Psoriasis

Psoriatic keratinocytes express exaggerated levels of inflammatory cytokines, and show aberrant hyperproliferation and terminal differentiation in the pathogenesis of psoriasis. The antimicrobial protein hS100A7 (psoriasin) has been found highly expressed in psoriatic skin, but the mechanism and phy...

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Detalles Bibliográficos
Autores principales: Lei, Hu, Li, Xiangyun, Jing, Bo, Xu, Hanzhang, Wu, Yingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218466/
https://www.ncbi.nlm.nih.gov/pubmed/28060905
http://dx.doi.org/10.1371/journal.pone.0169788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218466/
https://www.ncbi.nlm.nih.gov/pubmed/28060905
http://dx.doi.org/10.1371/journal.pone.0169788

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