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Preference of Conjugated Bile Acids over Unconjugated Bile Acids as Substrates for OATP1B1 and OATP1B3
Bile acids, the metabolites of cholesterol, are signaling molecules that play critical role in many physiological functions. They undergo enterohepatic circulation through various transporters expressed in intestine and liver. Human organic anion-transporting polypeptides (OATP) 1B1 and OATP1B3 cont...
Autores principales: | Suga, Takahiro, Yamaguchi, Hiroaki, Sato, Toshihiro, Maekawa, Masamitsu, Goto, Junichi, Mano, Nariyasu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218478/ https://www.ncbi.nlm.nih.gov/pubmed/28060902 http://dx.doi.org/10.1371/journal.pone.0169719 |
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