2-Phenylnaphthalene Derivatives Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Mediators by Downregulating of MAPK/NF-κB Pathways in RAW 264.7 Macrophage Cells

The anti-inflammatory pharmacological effect of eight 2-phenylnaphthalenes (PNAP-1−PNAP-8) on lipopolysaccharide (LPS)-induced RAW 264.7 (a mouse cell line) was investigated. Among them, 6,7-dihydroxy-2-(4′-hydroxyphenyl)naphthalene (PNAP-6) and 2-(4′-aminophenyl)-6,7-dimethoxynaphthalene (PNAP-8) e...

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Detalles Bibliográficos
Autores principales: Chang, Chi-Fen, Liao, Kang-Chun, Chen, Chung-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218479/
https://www.ncbi.nlm.nih.gov/pubmed/28060845
http://dx.doi.org/10.1371/journal.pone.0168945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218479/
https://www.ncbi.nlm.nih.gov/pubmed/28060845
http://dx.doi.org/10.1371/journal.pone.0168945

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