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Examining Sources of Error in PCR by Single-Molecule Sequencing

Next-generation sequencing technology has enabled the detection of rare genetic or somatic mutations and contributed to our understanding of disease progression and evolution. However, many next-generation sequencing technologies first rely on DNA amplification, via the Polymerase Chain Reaction (PC...

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Detalles Bibliográficos
Autores principales: Potapov, Vladimir, Ong, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218489/
https://www.ncbi.nlm.nih.gov/pubmed/28060945
http://dx.doi.org/10.1371/journal.pone.0169774