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Effect of a Soluble Epoxide Hydrolase Inhibitor, UC1728, on LPS-Induced Uveitis in the Rabbit

Cytochrome P450 epoxygenase isozymes convert free arachidonic acid into eicosanoids named epoxyeicosatrienoic acids (EETs) that have roles in regulating inflammation. EETs are rapidly converted to dihydroxyeicosatrienoic acids (DiHETs) by soluble epoxide hydrolase (sEH). Little is known about the po...

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Detalles Bibliográficos
Autores principales: McLellan, Gillian J., Aktas, Zeynep, Hennes-Beean, Elizabeth, Kolb, Aaron W., Larsen, Inna V., Schmitz, Emily J., Clausius, Hilary R., Yang, Jun, Hwang, Sung Hee, Morisseau, Christophe, Inceoglu, Bora, Hammock, Bruce D., Brandt, Curtis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218821/
https://www.ncbi.nlm.nih.gov/pubmed/28066796