Triazole RGD antagonist reverts TGFβ1-induced endothelial-to-mesenchymal transition in endothelial precursor cells

Fibrosis is the dramatic consequence of a dysregulated reparative process in which activated fibroblasts (myofibroblasts) and Transforming Growth Factor β1 (TGFβ1) play a central role. When exposed to TGFβ1, fibroblast and epithelial cells differentiate in myofibroblasts; in addition, endothelial ce...

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Detalles Bibliográficos
Autores principales: Bianchini, Francesca, Peppicelli, Silvia, Fabbrizzi, Pierangelo, Biagioni, Alessio, Mazzanti, Benedetta, Menchi, Gloria, Calorini, Lido, Pupi, Alberto, Trabocchi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219041/
https://www.ncbi.nlm.nih.gov/pubmed/27761847
http://dx.doi.org/10.1007/s11010-016-2847-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219041/
https://www.ncbi.nlm.nih.gov/pubmed/27761847
http://dx.doi.org/10.1007/s11010-016-2847-2

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